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KOWA 301

Posted on December 21, 2023

A Double-Masked, Randomized, Placebo-Controlled, Parallel-Group, 12-Week Administration With Two-Week Gradual Dose Taper Phase and 38-Week Follow-Up Phase, Phase 3 Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Descemetorhexis in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD).

Posted in Actively Recruiting, Clinical Trials, Cornea, Evan Warner, Fuchs Dystrophy

AURA 301

Posted on December 20, 2023

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects with Primary Intermediate Lesions or Small Choroidal Melanoma.

Posted in Actively Recruiting, Choroidal Melanoma, Clinical Trials, Intermediate Lesions, Melanoma, Michael Altaweel

NAC Attack

Posted on December 20, 2023

NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double-Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients with Retinitis Pigmentosa.

Posted in Actively Recruiting, Clinical Trials, Inherited Retinal Degeneration, Kimberly Stepien, Retinitis Pigmentosa

UNI-RARE

Posted on December 20, 2023

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated with Rare Disease-Causing Genetic Variants.

Posted in Actively Recruiting, Clinical Trials, Inherited Retinal Degeneration, Kimberly Stepien, Retinal Dystrophy

IMVT TED Extension

Posted on December 20, 2023

An Open-Label Extension Study for Participants who Completed Study IMVT-1401-3201 or Study IMVT-1401-3202 to Assess the Efficacy and Safety of Batoclimab for the Treatment of Thyroid Eye Disease (TED)

Posted in Actively Recruiting, Clinical Trials, Oculoplastics, Suzanne Van Landingham, Thyroid Eye Disease

QUASAR

Posted on December 20, 2023

Randomized, Double-Masked, Active-Controlled, Phase 3 Study of the Efficacy and Safety of Aflibercept 8 mg in Macular Edema Secondary to Retinal Vein Occlusion.

Posted in Actively Recruiting, Clinical Trials, Mihai Mititelu, Ongoing, Retinal Vein Occlusion

Robust real-time estimation of non-uniform angular velocity and sub-pixel jitter in images captured with resonant scanners.

Posted on December 18, 2023

PubMed ID: 38178497 Author(s): Ayubi GA, Dubra A. Robust real-time estimation of non-uniform angular velocity and sub-pixel jitter in images captured with resonant scanners. Opt Express. 2023 Dec 18;31(26):44199-44211. doi: 10.1364/OE.512233. PMID 38178497 Journal: Optics …

Posted in Alfredo Dubra, Publications

A non-conducting role of the Ca v 1.4 Ca 2+ channel drives homeostatic plasticity at the cone photoreceptor synapse.

Posted on December 6, 2023

PubMed ID: 38106079 Author(s): Maddox JW, Ordemann GJ, Vazquez JR, Huang A, Gault C, Wisner SR, Randall K, Futagi D, DeVries SH, Hoon M, Lee A. A non-conducting role of the Ca v 1.4 Ca …

Posted in Hoon Lab, Publications

Reticular Pseudodrusen: Interreader Agreement of Evaluation on OCT Imaging in Age-Related Macular Degeneration.

Posted on December 1, 2023

PubMed ID: 37292179 Author(s): Wu Z, Schmitz-Valckenberg S, Blodi BA, Holz FG, Jaffe GJ, Liakopoulos S, Sadda SR, Bonse M, Brown T, Choong J, Clifton B, Corradetti G, Corvi F, Dieu AC, Dooling V, Pak …

Posted in Barbara Blodi, Publications, WRC
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