PubMed ID: 42265079 Author(s): Shahi PK, Akyuz E, Gissot L, Al Saneh A, Pillala SK, Sinha D, Hanstad GM, Kabra M, Fernandez Zepeda MA, Gamm DM, Young SM, Ahern CA, Pattnaik BR. Engineered tRNA reduces …
Bikash Pattnaik
Association of Autosomal Dominant Snowflake Vitreoretinal Degeneration with Retinoschisis.
PubMed ID: 42199967 Author(s): Pattnaik BR, Nischal KK, Alekseev O, Williams S, Iannaccone A, Alabek M, Akyuz E, Eldib A, Kabra M, Aslan FS, Vajzovic L, Carmichael B, Ma Z, Jiao X, Hejtmancik JF. Association …
Mitofusins are required for specialized mitochondrial morphology and function of rod photoreceptor cells.
PubMed ID: 42317270 Author(s): Landowski M, Hagimori R, Gogoi P, Shahi PK, Oikawa K, Bhute VJ, McLellan GJ, Ikeda S, Yamada KI, Pattnaik BR, Takimoto T, Ikeda A. Mitofusins are required for specialized mitochondrial morphology …
Synonymous editing alters ion channel function, favoring prime editing for retinal disease correction.
PubMed ID: 42157932 Author(s): Kabra M, Moosajee M, Navarrete A, Newby GA, Rawding P, Xie R, Mechoulam H, Rivera A, Hung A, Tiwari S, Waxman AJ, Molugu K, Saha K, Gong S, Liu DR, Pattnaik …
Controlling CRISPR-Cas9 genome editing in human cells using a molecular glue degrader.
PubMed ID: 40799508 Author(s): Khajanchi N, Patel V, Dua R, Kabra M, Pattnaik BR, Saha K. Controlling CRISPR-Cas9 genome editing in human cells using a molecular glue degrader. Mol Ther Nucleic Acids. 2025 Jul 21;36(3):102640. …
Preventing vision loss in a mouse model of Leber Congenital Amaurosis by engineered tRNA.
PubMed ID: 40672310 Author(s): Akyuz E, Shahi PK, Gissot L, Al Saneh A, Sinha D, Hanstad GM, Kabra M, Zepeda MAF, Gamm DM, Young SM, Ahern CA, Pattnaik BR. Preventing vision loss in a mouse …
Divergent mechanisms of neural adaptation and instability in the mammalian retina.
PubMed ID: 40580962 Author(s): Khoussine J, Sawant A, Gupta S, Zhai H, Shahi PK, Pattnaik BR, Sinha R, Hoon M. Divergent mechanisms of neural adaptation and instability in the mammalian retina. Curr Biol. 2025 Jun …
Genome-Wide CRISPR Screening Identifies Cellular Factors Controlling Nonviral Genome Editing Efficiency.
PubMed ID: 40161775 Author(s): Saxena S, Kabra M, Abdeen A, Sinha D, Zhu M, Xie R, Hanstad G, Zepeda MAF, Gamm DM, Pattnaik BR, Gong S, Saha K. Genome-Wide CRISPR Screening Identifies Cellular Factors Controlling …
Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.
PubMed ID: 40554553 Author(s): Wei SC, Cantor AJ, Walleshauser J, Mepani R, Melton K, Bans A, Khekare P, Gupta S, Wang J, Soares C, Kiwan R, Lee J, McCawley S, Jani V, Leong WI, Shahi …