A current clinical trial could lead to approval of a first-ever treatment option for patients with geographic atrophy (GA) secondary to age-related macular degeneration, a progressive, irreversible, and devastating eye disease.
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Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures.
PubMed ID: 36598946 Author(s): Ludwig AL, Mayerl SJ, Gao Y, Banghart M, Bacig C, Fernandez Zepeda MA, Zhao X, Gamm DM. Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures. Proc Natl …
Lab-Grown Retinal Eye Cells Open Door For Clinical Trials to Treat Blindness
Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new study, completing a “handshake” that may show the cells are ready for trials in humans with degenerative eye disorders.
Inflammation, metabolic dysregulation and environmental neurotoxins and risk of cognitive decline and impairment in midlife.
PubMed ID: 36114981 Author(s): Schubert CR, Fischer ME, Pinto AA, Paulsen AJ, Chen Y, Huang GH, Klein BEK, Tsai MY, Merten N, Cruickshanks KJ. Inflammation, metabolic dysregulation and environmental neurotoxins and risk of cognitive decline …
The Relative Importance of Hospital Discharge and Patient Composition in Changing Post-Acute Care Utilization and Outcomes Among Medicare Beneficiaries.
PubMed ID: 37077324 Author(s): Cao YJ, Wang Y, Mullahy J, Burns M, Liu Y, Smith M. The Relative Importance of Hospital Discharge and Patient Composition in Changing Post-Acute Care Utilization and Outcomes Among Medicare Beneficiaries. …
Editorial: Insights in virus and host: 2021.
PubMed ID: 37113129 Author(s): Hiscott J, Brandt CR. Editorial: Insights in virus and host: 2021. Front Cell Infect Microbiol. 2023 Apr 11;13:1190338. doi: 10.3389/fcimb.2023.1190338. eCollection 2023. No abstract available. PMID 37113129 Journal: Frontiers In Cellular …
Disease parameters following ocular herpes simplex virus type 1 infection are similar in male and female BALB/C mice.
PubMed ID: 37319284 Author(s): Kolb AW, Ferguson SA, Larsen IV, Brandt CR. Disease parameters following ocular herpes simplex virus type 1 infection are similar in male and female BALB/C mice. PLoS One. 2023 Jun 15;18(6):e0287194. …
Associations of Midlife Lifestyle and Health Factors with Long-Term Changes in Blood-Based Biomarkers of Alzheimer’s Disease and Neurodegeneration.
PubMed ID: 37393497 Author(s): Merten N, Pinto AA, Paulsen AJ, Chen Y, Engelman CD, Hancock LM, Johnson SC, Schubert CR. Associations of Midlife Lifestyle and Health Factors with Long-Term Changes in Blood-Based Biomarkers of Alzheimer’s …
Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1Alpha (PGC-1α): A Transcriptional Regulator at the Interface of Aging and Age-Related Macular Degeneration?
PubMed ID: 37440013 Author(s): Mowat FM. Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1Alpha (PGC-1alpha): A Transcriptional Regulator at the Interface of Aging and Age-Related Macular Degeneration? Adv Exp Med Biol. 2023;1415:49-53. doi: 10.1007/978-3-031-27681-1_8. PMID 37440013 Journal: Advances …