Light stimulation of iris tyrosinase in vivo.

Publications // May 01 1980

PubMed ID: 6768692

Author(s): Dryja TP, Kimball GP, Albert DM. Light stimulation of iris tyrosinase in vivo. Invest Ophthalmol Vis Sci. 1980 May;19(5):559-62.

Journal: Investigative Ophthalmology & Visual Science, Volume 19, Issue 5, May 1980

Although exposure of epidermal melanocytes to ultraviolet radiation is known to increase tyrosinace activity, a similar effect has never been demonstrated for the iris. This paper presents evidence that light stimulates tyrosinase activity in iris melanocytes in rabbits. Levels of iris tyrosinase were found to be greater in eyes of rabbits exposed to light for 6 weeks than in eyes of rabbits maintained in darkness. Despite increasing tyrosinase levels, exposure to light produced to no clinically observable change in iris color.