Author(s): Cannistra AJ, Albert DM, Frambach DA, Dreher RJ, Roberts L. Sudden visual loss associated with clostridial bacteraemia. Br J Ophthalmol. 1988 May;72(5):380-5. PMID 3395597
Journal: The British Journal Of Ophthalmology, Volume 72, Issue 5, May 1988
A patient with endogenously acquired Clostridium septicum panophthalmitis is presented. The patient exhibited a striking sequence of signs and symptoms associated with this devastating ocular infection. Intensive antibiotic therapy was ineffective and enucleation of the globe was required. The microscopic pathology of the enucleated globe showed extensive infarction and necrosis of ocular structures in association with the panophthalmitis. In addition thrombosis of the central retinal artery and of choroidal vessels was observed.