PubMed ID: 32700445 Author(s): Tao Y, Cao J, Li M, Hoffmann B, Xu K, Chen J, Lu X, Guo F, Li X, Phillips MJ, Gamm DM, Chen H, Zhang SC. PAX6D instructs neural retinal specification …
Gamm Lab
Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution.
PubMed ID: 32707075 Author(s): Aboualizadeh E, Phillips MJ, McGregor JE, DiLoreto DA Jr, Strazzeri JM, Dhakal KR, Bateman B, Jager LD, Nilles KL, Stuedemann SA, Ludwig AL, Hunter JJ, Merigan WH, Gamm DM, Williams DR. …
Human iPSC Modeling Reveals Mutation-Specific Responses to Gene Therapy in a Genotypically Diverse Dominant Maculopathy.
PubMed ID: 32707085 Author(s): Sinha D, Steyer B, Shahi PK, Mueller KP, Valiauga R, Edwards KL, Bacig C, Steltzer SS, Srinivasan S, Abdeen A, Cory E, Periyasamy V, Siahpirani AF, Stone EM, Tucker BA, Roy …
Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level.
PubMed ID: 32483256 Author(s): Udry F, Decembrini S, Gamm DM, Déglon N, Kostic C, Arsenijevic Y. Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein …
A combined RNA-seq and whole genome sequencing approach for identification of non-coding pathogenic variants in single families.
PubMed ID: 32011687 Author(s): Bronstein R, Capowski EE, Mehrotra S, Jansen AD, Navarro-Gomez D, Maher M, Place E, Sangermano R, Bujakowska KM, Gamm DM, Pierce EA. A combined RNA-seq and whole genome sequencing approach for …
Investigating cone photoreceptor development using patient-derived NRL null retinal organoids.
PubMed ID: 32081919 Author(s): Kallman A, Capowski EE, Wang J, Kaushik AM, Jansen AD, Edwards KL, Chen L, Berlinicke CA, Joseph Phillips M, Pierce EA, Qian J, Wang TH, Gamm DM, Zack DJ. Investigating cone …
The Role of FGF9 in the Production of Neural Retina and RPE in a Pluripotent Stem Cell Model of Early Human Retinal Development.
PubMed ID: 31078532 Author(s): Gamm DM, Clark E, Capowski EE, Singh R. The role of FGF9 in the production of neural retina and RPE in a pluripotent stem cell model of early human retinal development. …
Gene Augmentation and Readthrough Rescue Channelopathy in an iPSC-RPE Model of Congenital Blindness.
PubMed ID: 30686507 Author(s): Shahi PK, Hermans D, Sinha D, Brar S, Moulton H, Stulo S, Borys KD, Capowski E, Pillers DM, Gamm DM, Pattnaik BR. Gene augmentation and readthrough rescue channelopathy in an iPSC-RPE …
Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines.
PubMed ID: 30567931 Author(s): Capowski EE, Samimi K, Mayerl SJ, Phillips MJ, Pinilla I, Howden SE, Saha J, Jansen AD, Edwards KL, Jager LD, Barlow K, Valiauga R, Erlichman Z, Hagstrom A, Sinha D, Sluch …